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OmicsBox Functional Analysis Module
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| SKU | omicsbox-functional-analysis |
|---|---|
| Status | Enabled |
High-Throughput Blast and InterProScan
Use CloudBlast and CloudInterProScan to perform fast sequence alignments and domain searches against reference datasets of your choice.
Gene Ontology Mapping
Link potential homologs and domains with available functional annotation from up-to-date well-curated databases from UniProt and Gene Ontology consortia.
Blast2GO Annotation
The Blast2GO methodology allows to flexibly assign most reliable functional labels to novel sequence datasets, taking into account source annotation quality and ontology hierarchies.
Enrichment Analysis
Use different enrichment analysis approaches (Fisher Exact Test and GSEA) to identify over and under represented molecular functions.
Combined Pathway Analysis
Identify Reactome and KEGG pathways for any set of sequences, use differential expression data to calculate pathway enrichment (GSEA) and a combined visualization to gain insights with ease.
Blast2GO Methodology
The well known Blast2GO annotation methodology, first published in 2005, is now part of OmicsBox. Blast2GO is the leading bioinformatics platform for the analysis of novel genomes, internationally recognized by the scientific community with over 7000+ research citations.
Everything in One Place
Load a FASTA file and analyze it step by step with the Blast2GO methodology to obtain high-quality functional annotations. All data in one place with full control over all analysis parameters.
Gene Set Enrichment Analysis
Convenient histograms and distribution charts help you to evaluate every stage in your analysis to get the most out of your data.
Gene Ontology Graphs
Visualize the annotations as GO graphs to get a good overview. In continuation, filter and shape the graph to bring out and present your conclusions clearly and neat.
Combined Pathway Analysis
This tool allows to identify pathways from multiple pathway databases for any set of sequences. In combination with differential expression data the tool allows to calculate pathway enrichment. A result table allows to filter for enriched pathways with linked, differentially expressed, genes.